Images from the Champions League matches played on Tuesday
Inter Milan's aversion to Europa League football continued with a 3-1 defeat at Sparta Prague, while AS Roma ended a continental hoodoo stretching back seven games with a 4-0 home win over Romanian side FC Astra on Thursday.
Watford climbed into the top four of the Premier League after Tom Cleverley's 92nd-minute goal gave them a 2-1 victory over Arsenal at Vicarage Road on Saturday.
While Lyon rallied to hold Leipzig 2-2 after a Memphis Depay strike, it was the English clubs who made a mark on the night. Liverpool and Chelsea moved into the last 16 with contrasting wins and now all four English clubs, including Manchester City and Tottenham Hotspur, are in the Champions League knockouts this season.
Images from the English Premier League matches played on Wednesday.
IMAGES from the English Premier League matches played on Saturday.
Real Madrid's Cristiano Ronaldo was the scourge of AS Roma again as he inspired the hosts to a 2-0 win and a place in the Champions League quarter-finals on Tuesday, scoring and setting up a goal Rodriguez to seal a 4-0 aggregate victory.
IMAGES from the English Premier League matches played on Saturday
A round-up of Wednesday's night's UEFA Chmpions League matches.
News of all that's transpired on and off the football field
City, who have a 16-point lead, can win the Premier League title with a victory over Jose Mourinho's side at the Etihad Stadium on Saturday, but after their 3-0 loss to Liverpool in the Champions League on Wednesday, Guardiola said the players needed a lift.
La Liga champions Real Madrid beat Getafe 3-1 on Saturday with a goal from Gareth Bale and two strikes from Cristiano Ronaldo to go 12 points behind leaders Barcelona and warm up for next week's Champions League game at Paris St Germain.
Here are talking points from the weekend's Premier League action:
IMAGES from the English Premier League match played on Saturday
Ahead of their high-profile clash on Saturday, check out the five standout clashes between Arsenal and Chelsea.
images from the UEFA Champions League matches played across Europe on Wednesday
Liverpool took over at the top of the Premier League table despite being held to a 0-0 draw against Manchester United in a scrappy match on Sunday.
With Liverpool still to visit Chelsea, who trail them by nine points with two games in hand, Juergen Klopp's side may have to beat Brighton & Hove Albion on May 13 and rely on their superior goal difference to qualify for the Champions League, assuming they do not secure it by winning this year's trophy.
Images from the English Premier League matches played on Saturday.
Ethiopia ended the hopes of 2010 World Cup hosts South Africa from making next year's finals in Brazil after a dramatic round of African group stage qualifying matches on Sunday.
Injuries have blighted Liverpool's start but Adam Lallana is back in full training after damaging his thigh pre-season and is expected to feature while another injury concern, Sadio Mane, also trained on Wednesday after tweaking a hamstring on international duty with Senegal.
Tottenham moved up to seventh place with 36 points from 22 games
Images from English Premier League matches played on Sunday.
After falling 2-0 down on the night, substitute Marcos Llorente struck twice in extra-time and Alvaro Morata added a late third to ensure a famous victory for Diego Simeone's side against a Liverpool team unbeaten in their last 25 home games in European competition.
Jose Mourinho said he was sad to see midfielder Juan Mata leaving Stamford Bridge after confirming that the Spaniard's move to Manchester United was imminent on Friday.
This and more from the happenings in the world of football
Images from Sunday's action in the Premier League.
Images from the English Premier League matches on Saturday.
Photos from the Premier League matches played on Sunday
Barcelona's Lionel Messi rescued a 1-1 draw at Villarreal with a sensational late free-kick on Sunday but could not prevent the champions finishing the weekend third in La Liga, five points behind leaders Real Madrid.
Images from Saturday's action in the English Premier League.
Sergio Aguero scored a hat-trick as free-scoring Manchester City climbed to the top of the Premier League with an irresistible 6-0 victory against Watford on Saturday.
Liverpool surrendered a two-goal lead as they were held to a 2-2 draw by third-tier Shrewsbury Town in the FA Cup fourth round on Sunday after second-half substitute Jason Cummins struck twice to inject some much-needed late magic into the competition. Earlier, Harry Maguire's thunderbolt for Manchester United started a goal rush at Tranmere where the Reds scored five times before halftime. Diogo Dalot, Jesse Lingard, Phil Jones, Anthony Martial and Mason Greenwood also scored.
Ole Gunnar Solskjaer continued his dream start as Manchester United caretaker manager with a 3-1 Premier League win over Huddersfield on his Old Trafford debut in the dugout on Wednesday.
Liverpool moved into the Champions League qualifying spots after a 3-0 win at Burnley on Wednesday took them above Leicester City and into fourth place with one round of Premier League matches remaining.
Atletico Madrid got their La Liga campaign up and running in less than convincing fashion when Antoine Griezmann's deflected free kick secured an edgy 1-0 win at home to promoted Las Palmas on Saturday.
Teenager Curtis Jones grabbed a 58th-minute winner as an injury-hit Liverpool qualified for the knockout stage of the Champions League with a 1-0 win over Ajax Amsterdam at Anfield on Tuesday.
Barca captain Messi opened the scoring with a "Panenka" penalty chipped straight down the middle in the 17th minute after Luis Suarez was fouled in the area, putting the home side ahead in the tie after a goalless first leg in France.
Images from Wednesday's action in the UEFA Champions League.
Alex Oxlade-Chamberlain became the second England international to leave Arsenal in two days when he joined Premier League rivals Liverpool for a reported 40 million pounds on Thursday.